Biochemistry

Prof. Pisit Tangkijvanich, M.D.

Position: Lecturer

Expertise:

  • Gastroenterology
  • Hepatology

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Biography

        Professor Pisit Tangkijvanich is a distinguished and highly respected figure in the field of hepatology and liver research. He currently serves as the Head of the Center of Excellence in Hepatitis and Liver Cancer at the Department of Biochemistry, Faculty of Medicine, Chulalongkorn University. Prof. Tangkijvanich’s academic journey began at Chulalongkorn University, where he received his Bachelor’s Degree in Medicine in 1988. His commitment to advancing medical knowledge led him to pursue further specialization in gastroenterology. He completed his fellowship at the Gastroenterology Unit before advancing to a research fellowship in Molecular Hepatology at the Division of Digestive Disease, UCLA School of Medicine, USA. Currently, Prof. Tangkijvanich is a full professor at the Department of Biochemistry, Chulalongkorn University. His expertise and leadership extend beyond academia; he is also the esteemed President of the Thai Association for the Study of the Liver (THASL). Throughout his prolific career, Prof. Tangkijvanich has made significant contributions to the understanding of viral hepatitis B and C, hepatic fibrosis, cirrhosis, tumor markers, hepatocellular carcinoma, and gut microbiota. His research has been widely recognized and acclaimed, evidenced by the publication of over 255 papers, accumulating over 5,000 citations, and a Google h-index of 37. Prof. Tangkijvanich’s groundbreaking work and dedication to the field have not only advanced scientific knowledge but also improved clinical practices and patient outcomes. His contributions continue to inspire and guide future generations of researchers and clinicians in hepatology and liver disease.

Education

              M.D., Chulalongkorn University, Bangkok, Thailand                                               1982-1988

              Board of Internal Medicine, Thailand                                                                          1991-1994

              Board of Gastroenterology and Hepatology, Thailand                                         1994-1996

   Postgraduate Posts:

              General Physician, Bungkan Hospital, Nongkai Province                                       1988-1991

              Resident, Department of Medicine, Chulalongkorn University                             1991-1994

              Fellow, Gastroenterology Unit,                                                                                        1994-1996

                     Department of Medicine, Chulalongkorn University

              Research Fellow in Molecular Hepatology, Division of Digestive Disease,               1999-2001

                     UCLA School of Medicine, USA

   Academic Posts:

              Lecturer, Department of Biochemistry                                                               1997-1999

                     Faculty of Medicine, Chulalongkorn University

              Assistant Professor, Department of Biochemistry                                          1999-2005

                     Faculty of Medicine, Chulalongkorn University

              Associated Professor, Department of Biochemistry                                       2005-2010

                     Faculty of Medicine, Chulalongkorn University

              Professor, Department of Biochemistry                                                             2010-present

                     Faculty of Medicine, Chulalongkorn University

Awards

  • Outstanding Research Award, Chulalongkorn University (year 2003) 
  • High-Impact Publication Award, Chulalongkorn University (year 2008)
  • Outstanding Researcher Award, Chulalongkorn University (year 2009)
  • Outstanding National Researcher Award, National Research Council of Thailand (NRCT) (year 2013)
  • Outstanding Research Unit (RU) Award, Chulalongkorn University (year 2017)
  • Dean’s Award for Outstanding Research-driven Department, Faculty of Medicine, Chulalongkorn University (year 2022)

Publications

  1. Cost-utility analysis of atezolizumab combined with bevacizumab for unresectable hepatocellular carcinoma in Thailand (PLoS ONE, 2024, 19(3 March), e0300327)  
  2. Gut Microbiota in Patients with Non-Alcoholic Fatty Liver Disease without Type 2 Diabetes: Stratified by Body Mass Index (Int J Mol Sci. 2024 Feb 2;25(3):1807.) 
  3. ZNF469 is a profibrotic regulator of extracellular matrix in hepatic stellate cells (J Cell Biochem. 2024 May 5.) 
  4. Long-term benefit of DAAs on gut dysbiosis and microbial translocation in HCV-infected patients with and without HIV coinfection (Sci Rep. 2023 Sep 2;13(1):14413.) 
  5. First-in-human randomized study of RNAi therapeutic RG6346 for chronic hepatitis B virus infection (J Hepatol. 2023 Nov;79(5):1139-1149.) 
  6. Regional Differences in Clinical Presentation and Prognosis of Patients With Post-Sustained Virologic Response Hepatocellular Carcinoma (Clin Gastroenterol Hepatol. 2024 Jan;22(1):72-80.e4.) 
  7. Efficacy and safety of the siRNA JNJ-73763989 and the capsid assembly modulator JNJ-56136379 (bersacapavir) with nucleos(t)ide analogues for the treatment of chronic hepatitis B virus infection (REEF-1): a multicentre, double-blind, active-controlled, randomised, phase 2b trial (Lancet Gastroenterol Hepatol. 2023 Sep;8(9):790-802.) 
  8. Metabolic-Associated Fatty Liver Disease (MAFLD) is associated with immune activation, increased epicardial fat volume, and steatohepatitis among people with HIV in a Thai cohort HIV Med. 2023 Sep;24(9):1000-1012.) 
  9. An innovative wireless electrochemical card sensor for field-deployable diagnostics of Hepatitis B surface antigen (Sci Rep. 2023 Mar 2;13(1):3523.) 

Books

  • รศ.นพ.พิสิฐ ตั้งกิจวานิชย์ (2553). ไวรัสตับอักเสบบีและมะเร็งตับ (พิมพ์ครั้งที่ 1).

Related links

Liverchula
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