Biochemistry

Prof. Sittisak Honsawek, M.D., Ph.D.

Position: Lecturer

Expertise:

Bone and joint disease, degenerative joint diseases,
musculoskeletal system and spine, osteoarthritis,
intervertebral disc degeneration, osteoporosis,
stem cells, bone tissue engineering, bone graft substitutes,
and biochemical markers

Google Scholar

Biography

  • Associate Dean for Student Affairs, 2020-present 
  • Co-Editor of Asian Biomedicine, 2017-present 
  • Editor-in-Chief of the Chulalongkorn Medical Journal, 2016-present   
  • Editor-in-Chief of the Journal of Medical Bioscience, 2019-present 
  • Chair of the Medical Biochemistry Program, 2015-present 
  • Head of the ​​Center of Excellence in Osteoarthritis and Musculoskeleton, 2021-present 

Education

  • Doctor of Medicine                                                     Chulalongkorn University
  • Master of Science (Molecular Biology)                 Virginia Commonwealth University, USA
  • Doctor of Philosophy (Biomedical Sciences)     Old Dominion University, USA
  • Postdoctoral fellowship                                             Rothman Institute, Thomas Jefferson University, USA 
  • Diploma of the Thai Board of Orthopaedics        King Memorial Chulalongkorn Hospital

Awards

  • Award for Outstanding Oral Research Presentation at the 39th Annual Meeting of the Royal College of Orthopaedic Surgeons of Thailand, held at the Royal Cliff Hotel Group, Pattaya, October 20-22, 2017. 

  • Award for Outstanding Research Presentation, “50 Best Abstract Awards,” at the 2008 Annual Tissue Engineering and Regenerative Medicine International Society–European Chapter (TERMIS-EU 2008) Meeting, Porto, Portugal, June 22-26, 2008.

  • Outstanding Research Award in the Health Sciences, Ratchadaphiseksomphot Fund, 2021. 

  • Exemplary Teacher Award, Faculty Senate, Health Sciences Category, Chulalongkorn University, 2023. 

Publications

  1. Honsawek S, Bovornsethanant N, Woraruthai T, Vejchapipat P, Udomsinprasert W, Poovorawan Y. Elevated serum IL-34 is correlated with disease severity in patients with biliary atresia following Kasai portoenterostomy. Int Immunopharmacol. 2024 Jan 25;127:111356. doi: 10.1016/j.intimp.2023.111356. Epub 2023 Dec 15.PMID: 38103407 

  2. Saengsiwaritt W, Jittikoon J, Chaikledkaew U, Tawonsawatruk T, Honsawek S, Udomsinprasert W. Effect of vitamin D supplementation on circulating level of autophagosome protein LC3A, inflammation, and physical performance in knee osteoarthritis. Clin Transl Sci. 2023 Dec;16(12):2543-2556. doi: 10.1111/cts.13646. Epub 2023 Oct 2.PMID: 37749758  

  3. Udomsinprasert W, Ungsudechachai T, Wunthong S, Yuttanarad S, Jittikoon J, Honsawek S. Effect of galectin-3 on synovial inflammation in knee osteoarthritis via stimulating phosphatidylinositol-3-kinase/Akt pathway. Int Immunopharmacol. 2023 Sep;122:110673. doi: 10.1016/j.intimp.2023.110673. Epub 2023 Jul 22.PMID: 37481852 

  4. Dechsupa S, Yingsakmongkol W, Limthongkul W, Singhatanadgige W, Jitjumnong M, Honsawek S. Vitamin D Inadequacy Affects Skeletal Muscle Index and Physical Performance in Lumbar Disc Degeneration. Int J Mol Sci. 2023 Feb 5;24(4):3152. doi: 10.3390/ijms24043152.PMID: 36834562  

  5. Riewruja K, Aguglia AM, Hines S, Makarcyzk MJ, Honsawek S, Lin H. PEG Reinforced Scaffold Promotes Uniform Distribution of Human MSC-Created Cartilage Matrix. Gels. 2022 Dec 3;8(12):794. doi: 10.3390/gels8120794.PMID: 36547318 

  6. Nonsa-Ard R, Aneknan P, Tong-Un T, Honsawek S, Leelayuwat N. Effects of Irvingia gabonensis Extract on Metabolism, Antioxidants, Adipocytokines, Telomere Length, and Aerobic Capacity in Overweight/Obese Individuals. Nutrients. 2022 Nov 3;14(21):4646. doi: 10.3390/nu14214646.PMID: 36364907  

  7. Nonsa-Ard R, Aneknan P, Tong-Un T, Honsawek S, Leelayuwat C, Leelayuwat N. Telomere Length Is Correlated with Resting Metabolic Rate and Aerobic Capacity in Women: A Cross-Sectional Study. Int J Mol Sci. 2022 Nov 1;23(21):13336. doi: 10.3390/ijms232113336.PMID: 36362129  

  8. Saetan N, Honsawek S, Tanavalee A, Ngarmukos S, Yuktanandana P, Poovorawan Y. Association between Common Variants in VEGFA Gene and the Susceptibility of Primary Knee Osteoarthritis. Cartilage. 2022 Dec;13(4):66-76. doi: 10.1177/19476035221132260. Epub 2022 Oct 31.PMID: 36314121 

  9. Jitjumnong M, Chalermkitpanit P, Suantawee T, Dechsupa S, Vajarintarangoon L, Honsawek S. Telomere Shortening and Increased Oxidative Stress in Lumbar Disc Degeneration. Int J Mol Sci. 2022 Sep 4;23(17):10125. doi: 10.3390/ijms231710125.PMID: 36077523  

  10. Ungsudechachai T, Honsawek S, Jittikoon J, Udomsinprasert W. Clusterin exacerbates interleukin-1β-induced inflammation via suppressing PI3K/Akt pathway in human fibroblast-like synoviocytes of knee osteoarthritis. Sci Rep. 2022 Jun 15;12(1):9963. doi: 10.1038/s41598-022-14295-7.PMID: 35705674  

Books

  • Honsawek S. Principle of Medical Biochemistry. Bangkok: Chulalongkorn University Press; 2023.

  • Honsawek S, Parkpian V. Orthopaedic Basic Science. Bangkok: Chulalongkorn University Press; 2020.

  • Parkpian V, Honsawek S. Orthopaedic Spine. Bangkok: Chulalongkorn University Press; 2020.

  • Parkpian V, Honsawek S. Orthopaedic Oncology. Bangkok: Chulalongkorn University Press; 2020.

  • Parkpian V, Honsawek S. Orthopaedic Trauma. Bangkok: Chulalongkorn University Press; 2020. 

  • Parkpian V, Honsawek S. Orthopaedic Sports & Pediatrics. Bangkok: Chulalongkorn University Press; 2020.

  • Honsawek S. Cell Biology and Biochemistry of Bone. Bangkok: Chulalongkorn University Press; 2023.

  • Parkpian V, Honsawek S. Sports Medicine and Pediatrics. Bangkok: Chulalongkorn University Press; 2014.

  • Parkpian V, Honsawek S. SPINE: INJURIES AND DISORDERS. Bangkok: Chulalongkorn University Press; 2012.

  • Honsawek S, Parkpian V. TRAUMA: FRACTURES AND DISLOCATION. Bangkok: Chulalongkorn University Press; 2011.

  • Honsawek S. Bone Biology. Bangkok: Chulalongkorn University Press; 2010.

  • Honsawek S, Parkpian V. TUMORS AND SYSTEMIC DISEASES. Bangkok: Chulalongkorn University Press; 2010.

  • Honsawek S, Parkpian V. Basic Biomedical Sciences of Bone, Stem cells, and Tissue Engineering. Bangkok: Chulalongkorn University Press; 2006.

  • Honsawek S, Sawangkong C. Medical Cell Biology I: Biomolecules and Cells. Bangkok: Chulalongkorn University Press; 2006.

  • Honsawek S, Sawangkong C. Medical Cell Biology II: Mechanisms of Cells and Tissues. Bangkok: Chulalongkorn University Press; 2006.

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