Biochemistry

Asst. Prof. Thananya Thongtan, Ph.D.

Position: Lecturer

Expertise:

  • Cell Death
  • Bioethics

Google Scholar

Biography

        Experienced instructor for preclerkship medical students and graduate students in medical sciences  at Faculty of Medicine, Chulalongkorn University for over 20 years in biochemistry and cell signaling. I specialize in cell death at the molecular level, particularly in response to flavivirus infection. Besides, I also serve as a secretary to the institutional review board at Faculty of Medicine (Med Chula IRB) and member and assistant secretary of central research ethics committee which is central IRB of Thailand. AI ethics is the topic of my interest, especially in data confidentiality perspective. 

Education

  • Fellowship in research ethics, Human research subject protection and the function and structure of Institutional Review Board,  Middleton Foundation for Ethical Studies, Washington, USA 2015  
  • PhD (Molecular genetics & genetic engineering) Mahidol University, Thailand  2003 
  • MSc (Biochemistry & Biophysics) Oregon State University, USA 1997 
  • BSc  (Biochemistry) Chulalongkorn University, Thailand 1993 

Publications

  1. Thongtan T, Panyim S, Smith DR. Apoptosis in dengue virus infected liver cell lines HepG2 and Hep3B. J Med Virol. 2004 Mar;72(3):436-44. doi: 10.1002/jmv.20004. PMID: 14748067 
  2. Thongtan T, Cheepsunthorn P, Chaiworakul V, Rattanarungsan C, Wikan N, Smith DR. Highly permissive infection of microglial cells by Japanese encephalitis virus: a possible role as a viral reservoir. Microbes Infect. 2010 Jan;12(1):37-45. doi: 10.1016/j.micinf.2009.09.013. Epub 2009 Sep 26. PMID: 19786116 
  3. Wongtrakul J, Paemanee A, Wintachai P, Thepparit C, Roytrakul S, Thongtan T, Janphen K, Supparatpinyo K, Smith DR. Nevirapine induces apoptosis in liver (HepG2) cells. Asian Pac J Trop Med. 2016 Jun;9(6):547-53. doi: 10.1016/j.apjtm.2016.04.015. Epub 2016 Apr 16. PMID: 27262065. 
  4. Wongtrakul J, Thongtan T, Pannengpetch S, Wikan N, Kantamala D, Kumrapich B, Suwan W, Smith DR. Phosphoproteomic analysis of dengue virus infected U937 cells and identification of pyruvate kinase M2 as a differentially phosphorylated phosphoprotein. Sci Rep. 2020 Sep 2;10(1):14493. doi: 10.1038/s41598-020-71407-x. PMID: 32879337; PMCID: PMC7467932 
  5. Wongtrakul J, Thongtan T, Kumrapich B, Saisawang C, Ketterman AJ. Neuroprotective effects of Withania somnifera in the SH-SY5Y Parkinson cell model. Heliyon. 2021 Oct 13;7(10):e08172. doi: 10.1016/j.heliyon.2021.e08172. PMID: 34765761; PMCID: PMC8569401. 

 

Books

  • ธนัญญา ทองตัน “เมแทบอลิซึมของนิวคลีโอไทด์ “ หลักชีวเคมีทางการแพทย์ หน้า 147-159  พิมพ์ครั้งที่ 2 กรุงเทพฯ สำนักพิมพ์จุฬาลงกรณ์มหาวิทยาลัย พศ. 2563-2566 
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