Asst. Prof. Chanchai Boonla, Ph.D.
Position: Lecturer
Email: Chanchai.b@chula.ac.th
Expertise:
- Oxidative stress and epigenetics in urolithiasis and cancers.
- Research and development of innovative diagnostic and therapeutic products.
Biography
By training, I am a medical technologist, graduated (B.Sc.) from Faculty of Associated Medical Sciences, Khon Kaen University in 1999. I received a Ph.D. in Medical Biochemistry from Faculty of Medicine, Khon Kaen University in 2004. I started to work at Department of Biochemistry, Faculty of Medicine, Chulalongkorn University in 2004. I finished my postdoctoral training at University of Freiburg, Germany under the Alexander Humboldt Fellowship in 2009.
Education
- B.Sc. (Hons) Medical Technology Khon Kaen University, Thailand 1999
- Ph.D. Medical Biochemistry (RGJ-PhD program) Khon Kaen University, Thailand 2004
- Doctoral research training Biological Science University of Manchester, UK 2002
- Doctoral research training Biochemistry and Biophysics University of North Carolina at Chapel Hill, NC, USA 2003
- Postdoctoral fellow Molecular Embryology (Humboldt Fellowship) University of Freiburg, Germany 2009
Awards
- Outstanding graduate alumni (Academic & Research) in 2015 from Faculty of Medicine, Khon Kaen University
- Outstanding graduate alumni (Academic & Research) in 2022 from Graduate School, Khon Kaen University
Publications
- Paolo Di Gianvincenzo, Marcos Fernandez Leyes, Kamonchat Boonkam, Alejandro Fábrega Puentes, Santiago Gimenez Reyes, Alessandro Nardini, Alessio Olivieri, Siwanut Pummarin, Nuntaporn Kamonsuttipaijit, Heinz Amenitsch, Hernan Ritacco, Marco D abramo, Maria Grazia Ortore, Chanchai Boonla, Sergio E. Moya. Supramolecular Citrate Poly allylamine hydrochloride Nanoparticles for citrate delivery and calcium oxalate nanocrystal dissolution. Journal of Colloid and Interface Science 2024
- Suchittra Phoyen, Anapat Sanpavat, Chakriwong Ma-on, Ulrike Stein, Nattiya Hirankarn, Pisit Tangkijvanich, Depicha Jindatip, Chanchai Boonla. H4K20me3 upregulated by reactive oxygen species is associated with tumor progression and poor prognosis in patients with hepatocellular carcinoma. Heliyon. 2023 Nov 20;9(12):e22589.
- Nalinthip Lordumrongkiat, Nattida Chotechuang, Mani Iyer Prasanth, Depicha Jindatip, Chakriwong Ma-on, Kamonchanok Chuenwisad, Asada Leelahavanichkul, Tewin Tencomnao, Chanchai Boonla. HydroZitLa inhibits calcium oxalate stone formation in nephrolithic rats and promotes longevity in nematode Caenorhabditis elegans. Sci Rep. 2022 Mar 24;12(1):5102.
- Kamonchanok Chuenwisad, Pimkanya More-Krong, Praween Tubsaeng, Nattida Chotechuang, Monpichar Srisa-Art, Robin J. Storer and Chanchai Boonla. Premature senescence and telomere shortening induced by oxidative stress from oxalate, calcium oxalate monohydrate, and urine from patients with calcium oxalate nephrolithiasis. Front. Immunol. 2021
- Pimkanya More-krong, Praween Tubsaeng, Natcha Madared, Monpichar Srisa-Art, Numpon Insin, Pannee Leeladee, Chanchai Boonla. Clinical validation of urinary indole-reacted calcium oxalate crystallization index (iCOCI) test for diagnosing calcium oxalate urolithiasis. Sci Rep 10, 8334 (2020).
- Whongsiri P, Pimratana C, Wijitsettakul U, Sanpavat A, Jindatip D, Hoffmann MJ, Goering W, Schulz WA, Boonla C. Oxidative stress and LINE-1 reactivation in bladder cancer are epigenetically linked through active chromatin formation. Free Radic Biol Med. 2019 Jan 29;134:419-428.
Books
- Chanchai Boonla. Chapter 7: Oxidative stress, epigenetics, and bladder cancer. In Preedy & Patel, Cancer: Oxidative Stress and Dietary Antioxidants, 2nd edition. 2021. Elsevier Academic Press. Pages 67-75
- Chanchai Boonla (May 23rd, 2018). Oxidative Stress in Urolithiasis, Reactive Oxygen Species (ROS) in Living Cells Filip Cristiana, IntechOpen