Biochemistry

Naphat Chantaravisoot, Ph.D.

Position: Lecturer

Expertise:

  • Systems Biology
  • Quantitative proteomics
  • Signal Transduction in Cancer

Google Scholar

Biography

        Dr. Naphat Chantaravisoot earned her Bachelor’s degree in Biology from Chulalongkorn University in 2008. As a DPST scholarship recipient, she pursued her Ph.D. at the University of California, Los Angeles, and graduated in 2015. Since late 2015, Dr. Naphat has been a member of the Biochemistry department, where her expertise lies in signal transduction in brain cancer cells, systems biology, quantitative proteomics, and phosphoproteomics. Dr. Naphat is dedicated to cultivating successful graduates. Currently affiliated with CUSM and CUSB, her research endeavors include unraveling cancer signaling pathways, particularly in brain cancer to discover novel biomarkers. She would like to translate her research findings into practical applications for patients, encompassing diagnostic tools, prognostic markers, and innovative drug development.

Education

  • Ph.D. in Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, California, USA, 2015
  • B.Sc. in Biology (1st Class Honors with Gold Medal) Chulalongkorn University, Bangkok, Thailand , 2008.

Awards

  • NRCT Invention Award (excellent level), National Research Council of Thailand, February 2022.
  • NRCT Dissertation Award (excellent level), National Research Council of Thailand, February 2020.  
  • Sidney Rittenberg Award for Ph.D. candidates, MIMG Department, University of California, Los Angeles, December 2014.
  • Outstanding Academic Record Award from The Professor Dr. Tab Nilanidhi Foundation (The Tab Foundation), Faculty of Science, Chulalongkorn University, August 2008.
  • Gold Medal from Chulalongkorn University (highest cumulative GPA in Department of Biology), July 2008.

Publications

  1. Chantaravisoot N, Wongkongkathep P, Kalpongnukul N, Pacharakullanon N, Kaewsapsak P, Chaiyaboot A, Loo JA, Tamanoi T, Pisitkun T. mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin. Scientific Reports. 2023 Apr 29;13(1):7037. 
  2. Kalpongnukul N, Bootsri R, Wongkongkathep P, Kaewsapsak P, Ariyachet C, Pisitkun T, Chantaravisoot N. Phosphoproteomic analysis defines BABAM1 as mTORC2 downstream effector promoting DNA damage response in glioblastoma cells. Journal of Proteome Research, 2022 Oct 21;13(1):7037. 
  3. Mayuramart O, Poomipak W, Rattanaburi S, Khongnomnan K, Anuntakarun S, Saengchoowong S,  Chavalit T, Chantaravisoot N, Payungporn S. IRF7-deficient MDCK cell based on CRISPR/Cas9 technology for enhancing influenza virus replication and improving vaccine production. PeerJ. 2022 Sep 21;10:e13989. 
  4. Kaewsapsak P, Chantaravisoot N, Nimsamer P, Mayuramart O, Mankhong S, Payungporn S. In Silico Evaluation of CRISPR-Based Assays for Effective Detection of SARS-CoV-2. Pathogens. 2022 Aug 25;11(9):968. 
  5. Ariyachet C, Chuaypen N, Kaewsapsak P, Chantaravisoot N, Jindatip D, Potikanond S, Tangkijvanich P. MicroRNA-223 Suppresses Human Hepatic Stellate Cell Activation Partly via Regulating the Actin Cytoskeleton and Alleviates Fibrosis in Organoid Models of Liver Injury. International Journal of Molecular Sciences. 2022 Aug 19;23(16):9380. 
  6. Chantaravisoot N, Kaewsapsak P, Mayuramart O, Nimsamer P, Mankhong S, Chomta N, Bootsri R, Alee I, Wongkongkathep P, Treeprasertsuk S, Payungporn S. COVID-19 active case findings based on self-collected saliva samples with CRISPR-Cas12a detection. Experimental Biology and Medicine. 2022 Apr 27:15353702221090181. 
  7. Wattanathamsan O, Chetprayoon P, Chantaravisoot N, Wongkongkathep P, Chanvorachote P, Pongrakhananon V. CAMSAP3 depletion induces lung cancer cell senescence‐associated phenotypes through extracellular signal-regulated kinase inactivation. Cancer medicine. 2021 Dec;10(24):8961-75. 
  8. Mayuramart O, Nimsamer P, Rattanaburi S, Chantaravisoot N, Khongnomnan K, Chansaenroj J, Puenpa J, Suntronwong N, Vichaiwattana P, Poovorawan Y, Payungporn S. Detection of severe acute respiratory syndrome coronavirus 2 and influenza viruses based on CRISPR-Cas12a. Experimental Biology and Medicine. 2021 Feb;246(4):400-5. 
  9. Thim-Uam A, Prabakaran T, Tansakul M, Makjaroen J, Wongkongkathep P, Chantaravisoot N, Saethang T, Leelahavanichkul A, Benjachat T, Paludan SR, Pisitkun T. STING mediates lupus via the activation of conventional dendritic cell maturation and plasmacytoid dendritic cell differentiation. Iscience. 2020 Sep 25;23(9):101530. 
  10. Chantaravisoot N, Wongkongkathep P, Loo JA, Mischel PS, Tamanoi F. Significance of filamin A in mTORC2 function in glioblastoma. Molecular cancer. 2015 Dec;14(1):1-14. 

Books

  • นพัต จันทรวิสูตร. “เมแทบอลิซึมของฮีม” หลักชีวเคมีทางการแพทย์ หน้า 209-216 กรุงเทพฯ: สำนักพิมพ์จุฬาลงกรณ์มหาวิทยาลัย พ.ศ. 2563-2566  
  • นพัต จันทรวิสูตร. “กระบวนการคัดลอก ซ่อมแซม และแลกเปลี่ยนดีเอ็นเอ” หลักชีวเคมีทางการแพทย์ หน้า 333-347 กรุงเทพฯ: สำนักพิมพ์จุฬาลงกรณ์มหาวิทยาลัย พ.ศ. 2563-2566  
  • นพัต จันทรวิสูตร. “สารพิษในอาหารและเมแทบอลิซึมของสารแปลกปลอม” หลักชีวเคมีทางการแพทย์ หน้า 259-271 กรุงเทพฯ: สำนักพิมพ์จุฬาลงกรณ์มหาวิทยาลัย พ.ศ. 2563-2566  
  • Chantaravisoot N, Tamanoi F. mTOR signaling and human cancer. The Enzymes (Vol. 28, pp. 301-316). Academic Press. 2010 Jan 1. 
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